LDN 91946

CAS No. 439946-22-2

LDN 91946 ( LDN91946 )

Catalog No. M14496 CAS No. 439946-22-2

LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 Get Quote
25MG 58 Get Quote
50MG 87 Get Quote
100MG 129 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    LDN 91946
  • Note
    Research use only, not for human use.
  • Brief Description
    LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM.
  • Description
    LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).
  • Synonyms
    LDN91946
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    DUB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    439946-22-2
  • Formula Weight
    316.32
  • Molecular Formula
    C17H12N6O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1(NC2=CC=CN=C2)=NC=C(C3=NC=NC=C3)C(C4=CC=CO4)=N1
  • Chemical Name
    3-amino-2-(benzoyl)-6-oxo-7H-thieno[3,2-e]pyridine-5-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mermerian AH, et al. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32.
2. Coulombe J, et al. Front Aging Neurosci. 2014 Jun 19;6:129.
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